The main requirement
MDF produces fine, abrasive dust. Router bit choice mainly depends on the required edge quality, extraction capacity and machine rigidity.
Three common geometries
An upcut bit moves chips upward. A downcut bit helps protect the top face. A compression bit combines both directions when material thickness and cutting length are compatible.
Before cutting
Check shank diameter, cutting length, clamping, extraction and the manufacturer maximum speed. Begin with a conservative pass on scrap and observe dust, sound and temperature.
Important
The stated parameters are starting points. Test progressively on scrap and always respect manufacturer limits.